Bone on ISS

Unsolved Issues for the Skeleton and Role of FG23-Klotho Axis; ​​ Contribution of a Bone Digital Twin
Bone on ISS

The ongoing Bone on ISS experiment studies the effects of microgravity on bone  health, focusing on bone loss and recovery post-spaceflight. By examining  bone markers, inflammation, and growth factors, the study aims to develop a digital twin model to predict bone behavior during recovery. This research is crucial for space missions, as it helps predict individual skeletal risks and  enables better astronaut screening. The findings will benefit Earth by advancing the understanding of bone disorders and improving treatments for  conditions like osteoporosis, helping populations prone to bone fragility and  immobility.

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