The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Space Diagnostics (Ax-1 CRISPR) tests CRISPR-based genetic identification on the Axiom-1 (Ax-1) private astronaut mission (PAM). CRISPR is a genome editing system that allows its users to detect and manipulate specific DNA and RNA sequences in living cells of diverse species. This technology could provide rapid and accurate detection of pathogens and contaminants on future long-term space missions.