DNA inspired Janus-based nanomaterials are biologically inspired nanotubes that can be used for therapeutic mRNA delivery or other therapeutics at room temperature, and as a first-in-kind injectable scaffold for cartilage repair. This project will leverage microgravity to optimize the assembly of DNA-based nanomaterials for multiple therapeutic uses and ultimately develop standards for in-space manufacturing of nanomaterials for a wide range of therapeutic applications. Axiom Space is contributing to the NASA-funded In-Space Production Applications project through the Ax-2 mission.