The TESH project from HUNOR aims to study the complex changes in astronauts' cardiovascular, musculoskeletal, and bone-muscle systems during space travel. By integrating the rdata from various medical devices with mission-specific data, and applying emerging data science techniques to analyze the information in near-realtime, the project aims to develop an AI-based medical data system that monitors astronaut health and supports mission planning.This project could also advance real-time health monitoring and predictive healthcare technologies on Earth.